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What Is CBDV (Cannabidivarin)? | Voluntate Shop

  • Writer: Mr Martin
    Mr Martin
  • Jan 26, 2023
  • 3 min read

It's simple to focus just on THC and CBD when discussing the many components of cannabis. After all, these are the plant's primary components. In spite of their tiny number, the hundreds of chemicals found in cannabis can significantly alter how the plant affects us. One such substance is cannabidivarin, or CBDV Isolate.

The cannabis debate has been dominated by THC and CBD. There are hundreds of different compounds in this ancient plant, many of which interact in interesting ways to provide countless advantages. Cannabivarin, often known as CBDV, is a cannabinoid with a lot of potentials that will be examined in detail in this article.

Describe CBDV.

One of the more than 100 cannabinoids that the cannabis plant produces is CBDV. Similar to other "secondary" cannabinoids, CBDV is normally present in lesser amounts than THC and CBD and is most prevalent in low-THC cannabis strains like hemp.

Since CBDV Isolate is not a psychoactive cannabinoid, it does not result in the euphoric high or drowsy stone that we often associate with cannabis strains strong in THC. The chemical structures and mechanisms of action of CBD and CBDV are strikingly similar, and we shall go into more detail about these similarities below.


The important part of how we perceive temperature and feel discomfort. Other research suggests that TRPV2 and TRPA1 receptors may be affected by CBDV.

These receptors are all transient receptor potential channels, according to research2 These channels, which are a part of the cell membrane, open up when activated to let ions—like sodium, for instance—flow into the cell. Additionally, studies indicate that CBDV Isolate may hinder the activity of diacylglycerol lipase, a crucial enzyme in the production of 2-AG, an endocannabinoid made by the body naturally. CBDV does this, but it's not fully clear how






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How Does CBDV Function?

There is still a lot we don't know about CBDV and its modes of action, much like with many cannabinoids. We do, however, have a general understanding of how this cannabinoid might behave in the human body based on early studies.

The cannabinoid receptors CB1 and CB2 do not exhibit a strong affinity for CBDV, similar to its cannabinoid relative (CBD). One of the key causes for why it doesn't have the intoxication effects generally linked with cannabis is because of this.


Cannabidivarin, like CBD, may function on additional chemical pathways and interact with the human endocannabinoid system in a much more indirect way, according to studies. Clinical trials[1] examining the effectiveness of CBDV Isolate in the treatment of convulsions and epilepsy symptoms, for instance, indicate that CBDV both activates and desensitizes TRPV1 receptors, also known as capsaicin receptors, which are essential for our ability to feel pain and perceive temperature. Other research suggests that TRPV2 and TRPA1 receptors may be affected by CBDV.

These receptors are all transient receptor potential channels, according to research2 These channels, which are a part of the cell membrane, open up when activated to let ions—like sodium, for instance—flow into the cell.

The Rett Syndrome and CBDV

Rett syndrome is a rare genetic abnormality that primarily affects women and impairs brain development. The condition is characterized by severe impairments that may impair a person's capacity for speaking, body coordination, healthy growth and development, and other functions.

Researchers decided to evaluate the efficacy of cannabis in the therapy of Rett syndrome since the endocannabinoid system mediates numerous biological functions that are compromised by this disorder. An animal model of Rett syndrome was used in a 2018 study that was published in the journal Neuropharmacology to explore the effects of CBDV Isolate. The mice's overall health, as well as behavioral impairment and brain shrinkage, had improved after 14 days of CBDV treatment, according to the researchers.


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